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Human Primary Cell-Based Organotypic Microtissues for Modeling Small Intestinal Drug Absorption
PURPOSE: The study evaluates the use of new in vitro primary human cell-based organotypic small intestinal (SMI) microtissues for predicting intestinal drug absorption and drug-drug interaction. METHODS: The SMI microtissues were reconstructed using human intestinal fibroblasts and enterocytes cultu...
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| Veröffentlicht in: | Pharm Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599640/ https://ncbi.nlm.nih.gov/pubmed/29476278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2362-0 |
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