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PRC2 proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Gene Expression at Promoter Regions in Euchromatin in Mice
BACKGROUND & AIMS: Little is known about mechanisms of postnatal hepatocyte maturation or chromatin regulation of genes that control fibrogenesis. We investigated transcription of genes that regulate fibrosis and the effects of chromatin compaction and the polycomb repressive complex 2 (PRC2) in...
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| Publicado no: | Gastroenterology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599454/ https://ncbi.nlm.nih.gov/pubmed/30689973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.01.041 |
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