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PRC2 proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Gene Expression at Promoter Regions in Euchromatin in Mice

BACKGROUND & AIMS: Little is known about mechanisms of postnatal hepatocyte maturation or chromatin regulation of genes that control fibrogenesis. We investigated transcription of genes that regulate fibrosis and the effects of chromatin compaction and the polycomb repressive complex 2 (PRC2) in...

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Detaylı Bibliyografya
Yayımlandı:Gastroenterology
Asıl Yazarlar: Grindheim, Jessica Mae, Nicetto, Dario, Donahue, Greg, Zaret, Kenneth S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599454/
https://ncbi.nlm.nih.gov/pubmed/30689973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.01.041
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