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Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1

Some adult-onset disorders may be linked to dysregulated embryonic development, yet the mechanisms underlying this association remain poorly understood. Congenital retinal degenerative diseases are blinding disorders characterized by postnatal degeneration of photoreceptors, and affect nearly 2 mill...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yan, Naihong, Cheng, Lin, Cho, Kinsang, Malik, Muhammad Taimur A., Xiao, Lirong, Guo, Chenying, Yu, Honghua, Zhu, Ruilin, Rao, Rajesh C., Chen, Dong Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039414/
https://ncbi.nlm.nih.gov/pubmed/27677711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33887
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