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Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1

Some adult-onset disorders may be linked to dysregulated embryonic development, yet the mechanisms underlying this association remain poorly understood. Congenital retinal degenerative diseases are blinding disorders characterized by postnatal degeneration of photoreceptors, and affect nearly 2 mill...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yan, Naihong, Cheng, Lin, Cho, Kinsang, Malik, Muhammad Taimur A., Xiao, Lirong, Guo, Chenying, Yu, Honghua, Zhu, Ruilin, Rao, Rajesh C., Chen, Dong Feng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039414/
https://ncbi.nlm.nih.gov/pubmed/27677711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33887
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