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Targeting EZH2 and PRC2 dependence as novel anticancer therapy
Distinctive patterns of chromatin modification control gene expression and define cellular identity during development and cell differentiation. Polycomb repressive complex 2 (PRC2), the sole mammalian enzymatic complex capable of establishing gene-repressive high-degree methylation of histone H3 at...
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| Опубликовано в: : | Exp Hematol |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706459/ https://ncbi.nlm.nih.gov/pubmed/26027790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.05.001 |
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