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Targeting EZH2 and PRC2 dependence as novel anticancer therapy

Distinctive patterns of chromatin modification control gene expression and define cellular identity during development and cell differentiation. Polycomb repressive complex 2 (PRC2), the sole mammalian enzymatic complex capable of establishing gene-repressive high-degree methylation of histone H3 at...

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Detalhes bibliográficos
Publicado no:Exp Hematol
Main Authors: Xu, Bowen, Konze, Kyle D., Jin, Jian, Wang, Gang Greg
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706459/
https://ncbi.nlm.nih.gov/pubmed/26027790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.05.001
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