Benefits of Caloric Restriction in Longevity and Chemical-Induced Tumorigenesis Are Transmitted Independent of NQO1

Caloric restriction (CR) is the most potent nonpharmacological intervention known to both protect against carcinogenesis and delay aging in laboratory animals. There is a growing number of anticarcinogens and CR mimetics that activate NAD(P)H:quinone oxidoreductase 1 (NQO1). We have previously shown...

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Publicat a:J Gerontol A Biol Sci Med Sci
Autors principals: Diaz-Ruiz, Alberto, Di Francesco, Andrea, Carboneau, Bethany A, Levan, Sophia R, Pearson, Kevin J, Price, Nathan L, Ward, Theresa M, Bernier, Michel, de Cabo, Rafael, Mercken, Evi M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
The Journal of Gerontology: Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6599277/
https://ncbi.nlm.nih.gov/pubmed/29733330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly112
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