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Structural basis of TFIIH activation for nucleotide excision repair
Nucleotide excision repair (NER) is the major DNA repair pathway that removes UV-induced and bulky DNA lesions. There is currently no structure of NER intermediates, which form around the large multisubunit transcription factor IIH (TFIIH). Here we report the cryo-EM structure of an NER intermediate...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6599211/ https://ncbi.nlm.nih.gov/pubmed/31253769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10745-5 |
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