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Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant
Adgrg6 (Gpr126) is an adhesion class G protein-coupled receptor with a conserved role in myelination of the peripheral nervous system. In the zebrafish, mutation of adgrg6 also results in defects in the inner ear: otic tissue fails to down-regulate versican gene expression and morphogenesis is disru...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6598766/ https://ncbi.nlm.nih.gov/pubmed/31180326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44889 |
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