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Targeted Protein Internalization and Degradation by ENDosome TArgeting Chimeras (ENDTACs)

[Image: see text] Targeted protein degradation has generated excitement in chemical biology and drug discovery throughout academia and industry. By hijacking the machinery responsible for protein degradation via the ubiquitin proteasome system (UPS), various cellular targets have been selectively de...

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Detalhes bibliográficos
Publicado no:ACS Cent Sci
Main Authors: Nalawansha, Dhanusha A., Paiva, Stacey-Lynn, Rafizadeh, Diane N., Pettersson, Mariell, Qin, Liena, Crews, Craig M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6598169/
https://ncbi.nlm.nih.gov/pubmed/31263767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00224
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