An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2

BACKGROUND: Mutations in LRRK2 are the most common cause of autosomal dominant Parkinson's disease, and the relevance of LRRK2 to the sporadic form of the disease is becoming ever more apparent. It is therefore essential that studies are conducted to improve our understanding of the cellular ro...

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Detaylı Bibliyografya
Yayımlandı:Neurobiol Dis
Asıl Yazarlar: Connor-Robson, Natalie, Booth, Heather, Martin, Jeffrey G., Gao, Benbo, Li, Kejie, Doig, Natalie, Vowles, Jane, Browne, Cathy, Klinger, Laura, Juhasz, Peter, Klein, Christine, Cowley, Sally A., Bolam, Paul, Hirst, Warren, Wade-Martins, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Academic Press 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597903/
https://ncbi.nlm.nih.gov/pubmed/30954703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.04.005
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