Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea

PIWI proteins are key regulators of germline and somatic stem cells throughout different evolutionary lineages. However, how PIWI proteins themselves are regulated remains largely unknown. To identify candidate proteins that interact with PIWI proteins and regulate their stability, here we establish...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Wang, Chen, Yang, Zhen-Zhen, Guo, Fang-Hao, Shi, Shuo, Han, Xiao-Shuai, Zeng, An, Lin, Haifan, Jing, Qing
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597837/
https://ncbi.nlm.nih.gov/pubmed/31076507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004445
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