Heat shock protein DNAJA1 stabilizes PIWI proteins to support regeneration and homeostasis of planarian Schmidtea mediterranea

PIWI proteins are key regulators of germline and somatic stem cells throughout different evolutionary lineages. However, how PIWI proteins themselves are regulated remains largely unknown. To identify candidate proteins that interact with PIWI proteins and regulate their stability, here we establish...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Wang, Chen, Yang, Zhen-Zhen, Guo, Fang-Hao, Shi, Shuo, Han, Xiao-Shuai, Zeng, An, Lin, Haifan, Jing, Qing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Developmental Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597837/
https://ncbi.nlm.nih.gov/pubmed/31076507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004445
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