Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis

During embryogenesis cells make fate decisions within complex tissue environments. The levels and dynamics of transcription factor expression regulate these decisions. Here, we use single cell live imaging of an endogenous HES5 reporter and absolute protein quantification to gain a dynamic view of n...

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Foilsithe in:Nat Commun
Main Authors: Manning, Cerys S., Biga, Veronica, Boyd, James, Kursawe, Jochen, Ymisson, Bodvar, Spiller, David G., Sanderson, Christopher M., Galla, Tobias, Rattray, Magnus, Papalopulu, Nancy
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597611/
https://ncbi.nlm.nih.gov/pubmed/31249377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10734-8
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