Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation

Recent studies suggest that cells make stochastic choices with respect to differentiation or division. However, the molecular mechanism underlying such stochasticity is unknown. We previously proposed that the timing of vertebrate neuronal differentiation is regulated by molecular oscillations of a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Phillips, Nick E, Manning, Cerys S, Pettini, Tom, Biga, Veronica, Marinopoulou, Elli, Stanley, Peter, Boyd, James, Bagnall, James, Paszek, Pawel, Spiller, David G, White, Michael RH, Goodfellow, Marc, Galla, Tobias, Rattray, Magnus, Papalopulu, Nancy
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2016
נושאים:
Computational and Systems Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050025/
https://ncbi.nlm.nih.gov/pubmed/27700985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.16118
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים