De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation

Transdifferentiation is a complete and stable change in cell identity that serves as an alternative to stem-cell-mediated organ regeneration. In adult mammals, findings of transdifferentiation have been limited to the replenishment of cells lost from preexisting structures, i.e., in the presence of...

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Publicado no:Nature
Main Authors: Schaub, Johanna R., Huppert, Kari A., Kurial, Simone N. T., Hsu, Bernadette Y., Cast, Ashley E., Donnelly, Bryan, Karns, Rebekah A., Chen, Feng, Rezvani, Milad, Luu, Hubert Y., Mattis, Aras N., Rougemont, Anne-Laure, Rosenthal, Philip, Huppert, Stacey S., Willenbring, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597492/
https://ncbi.nlm.nih.gov/pubmed/29720662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0075-5
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