Expression of hepatocytic- and biliary-specific transcription factors in regenerating bile ducts during hepatocyte-to-biliary epithelial cell transdifferentiation

BACKGROUND: Under compromised biliary regeneration, transdifferentiation of hepatocytes into biliary epithelial cells (BEC) has been previously observed in rats, upon exposure to BEC-specific toxicant methylene dianiline (DAPM) followed by bile duct ligation (BDL), and in patients with chronic bilia...

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Détails bibliographiques
Auteurs principaux: Limaye, Pallavi B, Bowen, William C, Orr, Anne, Apte, Udayan M, Michalopoulos, George K
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014870/
https://ncbi.nlm.nih.gov/pubmed/21126359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-9-9
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