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Oct4 Is Crucial for Transdifferentiation of Hepatocytes to Biliary Epithelial Cells in an In Vitro Organoid Culture Model

Hepatocyte to biliary transdifferentiation has been documented in various models of bile duct injury. In this process, mature hepatocytes transform into mature biliary epithelial cells by acquiring biliary phenotypic markers. Several signaling pathways including PI3 kinase, Notch, Hes1, Sox9, and Hi...

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Bibliografiska uppgifter
I publikationen:Gene Expr
Huvudupphovsmän: Doffou, Mboya, Adams, George, Bowen, William C., Paranjpe, Shirish, Parihar, Harish S., Nguyen, Huy, Michalopoulos, George K., Bhave, Vishakha S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cognizant Communication Corporation 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5885146/
https://ncbi.nlm.nih.gov/pubmed/29212575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221617X15124876321401
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