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Spermidine confers liver protection by enhancing NRF2 signaling through a MAP1S-mediated non-canonical mechanism

Spermidine, a naturally occurring polyamine, has been recognized as a caloric restriction mimetic that confers health benefits, presumably by inducing autophagy. Recent studies have reported that oral administration of spermidine protects against liver fibrosis and hepatocarcinogenesis through activ...

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Détails bibliographiques
Publié dans:Hepatology
Auteurs principaux: Liu, Pengfei, de la Vega, Montserrat Rojo, Dodson, Matthew, Yue, Fei, Shi, Boyun, Fang, Deyu, Chapman, Eli, Liu, Leyuan, Zhang, Donna D.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6597327/
https://ncbi.nlm.nih.gov/pubmed/30873635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30616
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