Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development

DNA repair is crucial for genome stability in the developing cortex, as somatic de novo mutations cause neurological disorders. However, how DNA repair contributes to neuronal development is largely unknown. To address this issue, we studied the spatiotemporal roles of DNA polymerase β (Polβ), a key...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Onishi, Kohei, Uyeda, Akiko, Shida, Mitsuhiro, Hirayama, Teruyoshi, Yagi, Takeshi, Yamamoto, Nobuhiko, Sugo, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596877/
https://ncbi.nlm.nih.gov/pubmed/28765330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0665-17.2017
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