Genome Stability by DNA Polymerase β in Neural Progenitors Contributes to Neuronal Differentiation in Cortical Development

DNA repair is crucial for genome stability in the developing cortex, as somatic de novo mutations cause neurological disorders. However, how DNA repair contributes to neuronal development is largely unknown. To address this issue, we studied the spatiotemporal roles of DNA polymerase β (Polβ), a key...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Onishi, Kohei, Uyeda, Akiko, Shida, Mitsuhiro, Hirayama, Teruyoshi, Yagi, Takeshi, Yamamoto, Nobuhiko, Sugo, Noriyuki
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596877/
https://ncbi.nlm.nih.gov/pubmed/28765330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0665-17.2017
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