Characterization of Arsenic Hepatobiliary Transport Using Sandwich-Cultured Human Hepatocytes

Arsenic is a proven human carcinogen and is associated with a myriad of other adverse health effects. This metalloid is methylated in human liver to monomethylarsonic acid (MMA(V)), monomethylarsonous acid (MMA(III)), dimethylarsinic acid (DMA(V)), and dimethylarsinous acid (DMA(III)) and eliminated...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Roggenbeck, Barbara A., Carew, Michael W., Charrois, Gregory J., Douglas, Donna N., Kneteman, Norman M., Lu, Xiufen, Le, X. Chris, Leslie, Elaine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Transport of Arsenic in Primary Human Hepatocytes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596447/
https://ncbi.nlm.nih.gov/pubmed/25752797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv051
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