Renal natural killer cell activation and mitochondrial oxidative stress; new mechanisms in AT1-AA mediated hypertensive pregnancy

Women with preeclampsia (PE) have increased mean arterial pressure (MAP), natural killer (NK) cells, reactive oxygen species (ROS), and agonistic autoantibodies to the angiotensin II type 1 receptor (AT1-AA). AT1-AA’s administered to pregnant rodents produces a well-accepted model of PE. However, th...

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Vydáno v:Pregnancy Hypertens
Hlavní autoři: Cunningham, Mark W., Vaka, Venkata Ramana, McMaster, Kristen, Ibrahim, Tarek, Cornelius, Denise C., Amaral, Lorena, Campbell, Nathan, Wallukat, Gerd, McDuffy, Shyanne, Usry, Nathan, Dechend, Ralf, LaMarca, Babbette
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596414/
https://ncbi.nlm.nih.gov/pubmed/30825931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preghy.2018.11.004
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