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A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline

In addition to treating depression, antidepressant drugs are also a first-line treatment for neuropathic pain, which is pain secondary to lesion or pathology of the nervous system. Despite the widespread use of these drugs, the mechanism underlying their therapeutic action in this pain context remai...

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Publicat a:J Neurosci
Autors principals: Kremer, Mélanie, Yalcin, Ipek, Goumon, Yannick, Wurtz, Xavier, Nexon, Laurent, Daniel, Dorothée, Megat, Salim, Ceredig, Rhian A., Ernst, Carl, Turecki, Gustavo, Chavant, Virginie, Théroux, Jean-François, Lacaud, Adrien, Joganah, Lauriane-Elisabeth, Lelievre, Vincent, Massotte, Dominique, Lutz, Pierre-Eric, Gilsbach, Ralf, Salvat, Eric, Barrot, Michel
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596240/
https://ncbi.nlm.nih.gov/pubmed/30249798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1004-18.2018
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