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Fluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors

G protein-coupled receptors (GPCRs) modulate most physiological functions but are also critically involved in numerous pathological states. Approximately a third of marketed drugs target GPCRs, which places this family of receptors in the main arena of pharmacological pre-clinical and clinical resea...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ceredig, Rhian A., Massotte, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284998/
https://ncbi.nlm.nih.gov/pubmed/25610398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00289
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