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Deciphering the Code to Aminergic G-Protein Coupled Receptor Drug Design
The trace amine-associated receptor 1 (TAAR(1)) is a biogenic amine G-protein coupled receptor (GPCR) that is potently activated by 3-iodothyronamine (1, T(1)AM) in vitro. Compound 1 is an endogenous derivative of the thyroid hormone thyroxine that rapidly induces hypothermia, anergia, and bradycard...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713717/ https://ncbi.nlm.nih.gov/pubmed/18420141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2008.03.004 |
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