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Functionalized Congener Approach to the Design of Ligands for G Protein–Coupled Receptors (GPCRs)
Functionalized congeners, in which a chemically functionalized chain is incorporated at an insensitive site on a pharmacophore, have been designed from the agonist and antagonist ligands of various G protein–coupled receptors (GPCRs). These chain extensions enable a conjugation strategy for detectin...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888900/ https://ncbi.nlm.nih.gov/pubmed/19405524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9000596 |
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