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The Molecular Basis of Species-Specific Ligand Activation of Trace Amine-Associated Receptor 1 (TAAR(1))

The trace amine-associated receptor 1 (TAAR(1)) is an aminergic G protein-coupled receptor (GPCR) potently activated by 3-iodothyronamine (1), an endogenous derivative of thyroid hormone. Structure activity relationship studies on 1 and related agonists showed that the rat and mouse species of TAAR(...

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Detalhes bibliográficos
Main Authors: Tan, Edwin S., Naylor, John C., Groban, Eli S., Bunzow, James R., Jacobson, Matthew P., Grandy, David K., Scanlan, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677188/
https://ncbi.nlm.nih.gov/pubmed/19256523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800304d
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