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A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline

In addition to treating depression, antidepressant drugs are also a first-line treatment for neuropathic pain, which is pain secondary to lesion or pathology of the nervous system. Despite the widespread use of these drugs, the mechanism underlying their therapeutic action in this pain context remai...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Kremer, Mélanie, Yalcin, Ipek, Goumon, Yannick, Wurtz, Xavier, Nexon, Laurent, Daniel, Dorothée, Megat, Salim, Ceredig, Rhian A., Ernst, Carl, Turecki, Gustavo, Chavant, Virginie, Théroux, Jean-François, Lacaud, Adrien, Joganah, Lauriane-Elisabeth, Lelievre, Vincent, Massotte, Dominique, Lutz, Pierre-Eric, Gilsbach, Ralf, Salvat, Eric, Barrot, Michel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596240/
https://ncbi.nlm.nih.gov/pubmed/30249798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1004-18.2018
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