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Parent-of-origin-specific allelic expression in the human placenta is limited to established imprinted loci and it is stably maintained across pregnancy

BACKGROUND: Genomic imprinting, mediated by parent-of-origin-specific epigenetic silencing, adjusts the gene expression dosage in mammals. We aimed to clarify parental allelic expression in the human placenta for 396 claimed candidate imprinted genes and to assess the evidence for the proposed enric...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Pilvar, Diana, Reiman, Mario, Pilvar, Arno, Laan, Maris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595585/
https://ncbi.nlm.nih.gov/pubmed/31242935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0692-3
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