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Parent-of-origin-specific allelic expression in the human placenta is limited to established imprinted loci and it is stably maintained across pregnancy

BACKGROUND: Genomic imprinting, mediated by parent-of-origin-specific epigenetic silencing, adjusts the gene expression dosage in mammals. We aimed to clarify parental allelic expression in the human placenta for 396 claimed candidate imprinted genes and to assess the evidence for the proposed enric...

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Publicat a:Clin Epigenetics
Autors principals: Pilvar, Diana, Reiman, Mario, Pilvar, Arno, Laan, Maris
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595585/
https://ncbi.nlm.nih.gov/pubmed/31242935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0692-3
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