CDYL Bridges REST and Histone Methyltransferases for Gene Repression and Suppression of Cellular Transformation

The neuronal gene repressor REST/NRSF recruits co-repressors, including CoREST, to modify histones and repress transcription. REST also functions as a tumor suppressor, but the mechanism remains unclear. We identified Chromodomain on Y-like (CDYL) as a REST co-repressor that physically bridges REST...

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Vydáno v:Mol Cell
Hlavní autoři: Mulligan, Peter, Westbrook, Thomas F., Ottinger, Matthias, Pavlova, Natalya, Chang, Bin, Macia, Eric, Shi, Yu-Jiang, Barretina, Jordi, Liu, Jinsong, Howley, Peter M., Elledge, Stephen J., Shi, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6595072/
https://ncbi.nlm.nih.gov/pubmed/19061646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.025
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