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Common and distinct transcriptional signatures of mammalian embryonic lethality

The Deciphering the Mechanisms of Developmental Disorders programme has analysed the morphological and molecular phenotypes of embryonic and perinatal lethal mouse mutant lines in order to investigate the causes of embryonic lethality. Here we show that individual whole-embryo RNA-seq of 73 mouse mu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Collins, John E., White, Richard J., Staudt, Nicole, Sealy, Ian M., Packham, Ian, Wali, Neha, Tudor, Catherine, Mazzeo, Cecilia, Green, Angela, Siragher, Emma, Ryder, Edward, White, Jacqueline K., Papatheodoru, Irene, Tang, Amy, Füllgrabe, Anja, Billis, Konstantinos, Geyer, Stefan H., Weninger, Wolfgang J., Galli, Antonella, Hemberger, Myriam, Stemple, Derek L., Robertson, Elizabeth, Smith, James C., Mohun, Timothy, Adams, David J., Busch-Nentwich, Elisabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594971/
https://ncbi.nlm.nih.gov/pubmed/31243271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10642-x
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