Mitochondrial and autophagic alterations in skin fibroblasts from Parkinson disease patients with Parkin mutations

PRKN encodes an E3-ubiquitin-ligase involved in multiple cell processes including mitochondrial homeostasis and autophagy. Previous studies reported alterations of mitochondrial function in fibroblasts from patients with PRKN mutation-associated Parkinson’s disease (PRKN-PD) but have been only condu...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: González-Casacuberta, Ingrid, Juárez-Flores, Diana-Luz, Ezquerra, Mario, Fucho, Raquel, Catalán-García, Marc, Guitart-Mampel, Mariona, Tobías, Ester, García-Ruiz, Carmen, Fernández-Checa, José Carlos, Tolosa, Eduard, Martí, María-José, Grau, Josep Maria, Fernández-Santiago, Rubén, Cardellach, Francesc, Morén, Constanza, Garrabou, Glòria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594812/
https://ncbi.nlm.nih.gov/pubmed/31180333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102014
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