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Predicting gastrointestinal drug effects using contextualized metabolic models

Gastrointestinal side effects are among the most common classes of adverse reactions associated with orally absorbed drugs. These effects decrease patient compliance with the treatment and induce undesirable physiological effects. The prediction of drug action on the gut wall based on in vitro data...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ben Guebila, Marouen, Thiele, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594586/
https://ncbi.nlm.nih.gov/pubmed/31242176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007100
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