GAD mRNA in Orbital Prefrontal Cortex and Anterior Cingulate Cortex in Alcoholics Compared with Nonpsychiatric Controls: A Negative Postmortem Study

Alcohol increases inhibitory neurotransmission, an effect mediated through GABA receptors. With chronic alcohol exposure, the inhibitory effects diminish. Glutamic acid decarboxylase (GAD) catalyzes glutamate in the synthesis of GABA. We sought to determine the amount of GAD(65/67) mRNA in anterior...

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Vydáno v:J Psychiatr Brain Sci
Hlavní autoři: Underwood, Mark D., Bakalian, Mihran J., Dwork, Andrew J., Min, Eli, Mann, J. John, Arango, Victoria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594560/
https://ncbi.nlm.nih.gov/pubmed/31245628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/jpbs.20190007
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