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GAD mRNA in Orbital Prefrontal Cortex and Anterior Cingulate Cortex in Alcoholics Compared with Nonpsychiatric Controls: A Negative Postmortem Study

Alcohol increases inhibitory neurotransmission, an effect mediated through GABA receptors. With chronic alcohol exposure, the inhibitory effects diminish. Glutamic acid decarboxylase (GAD) catalyzes glutamate in the synthesis of GABA. We sought to determine the amount of GAD(65/67) mRNA in anterior...

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Pubblicato in:J Psychiatr Brain Sci
Autori principali: Underwood, Mark D., Bakalian, Mihran J., Dwork, Andrew J., Min, Eli, Mann, J. John, Arango, Victoria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594560/
https://ncbi.nlm.nih.gov/pubmed/31245628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/jpbs.20190007
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