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GAD mRNA in Orbital Prefrontal Cortex and Anterior Cingulate Cortex in Alcoholics Compared with Nonpsychiatric Controls: A Negative Postmortem Study

Alcohol increases inhibitory neurotransmission, an effect mediated through GABA receptors. With chronic alcohol exposure, the inhibitory effects diminish. Glutamic acid decarboxylase (GAD) catalyzes glutamate in the synthesis of GABA. We sought to determine the amount of GAD(65/67) mRNA in anterior...

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Dades bibliogràfiques
Publicat a:J Psychiatr Brain Sci
Autors principals: Underwood, Mark D., Bakalian, Mihran J., Dwork, Andrew J., Min, Eli, Mann, J. John, Arango, Victoria
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594560/
https://ncbi.nlm.nih.gov/pubmed/31245628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/jpbs.20190007
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