Less NMDA Receptor Binding in Dorsolateral Prefrontal Cortex and Anterior Cingulate Cortex Associated With Reported Early-Life Adversity but Not Suicide

BACKGROUND: Glutamate is an excitatory neurotransmitter binding to 3 classes of receptors, including the N-methyl, D-aspartate (NMDA) receptor. NMDA receptor binding is lower in major depression disorder and suicide. NMDA receptor blocking with ketamine can have antidepressant and anti-suicide effec...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Underwood, Mark D, Bakalian, Mihran J, Johnson, Virginia L, Kassir, Suham A, Ellis, Steven P, Mann, J John, Arango, Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Regular Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251634/
https://ncbi.nlm.nih.gov/pubmed/32060512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyaa009
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