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GAD mRNA in Orbital Prefrontal Cortex and Anterior Cingulate Cortex in Alcoholics Compared with Nonpsychiatric Controls: A Negative Postmortem Study

Alcohol increases inhibitory neurotransmission, an effect mediated through GABA receptors. With chronic alcohol exposure, the inhibitory effects diminish. Glutamic acid decarboxylase (GAD) catalyzes glutamate in the synthesis of GABA. We sought to determine the amount of GAD(65/67) mRNA in anterior...

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Detalhes bibliográficos
Publicado no:J Psychiatr Brain Sci
Main Authors: Underwood, Mark D., Bakalian, Mihran J., Dwork, Andrew J., Min, Eli, Mann, J. John, Arango, Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594560/
https://ncbi.nlm.nih.gov/pubmed/31245628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/jpbs.20190007
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