Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis

Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to contribute to its pathogenesis. In the present stud...

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Udgivet i:Front Immunol
Main Authors: Meiners, Jana, Palmieri, Vittoria, Klopfleisch, Robert, Ebel, Jana-Fabienne, Japtok, Lukasz, Schumacher, Fabian, Yusuf, Ayan Mohamud, Becker, Katrin A., Zöller, Julia, Hose, Matthias, Kleuser, Burkhard, Hermann, Dirk M., Kolesnick, Richard N., Buer, Jan, Hansen, Wiebke, Westendorf, Astrid M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594205/
https://ncbi.nlm.nih.gov/pubmed/31275322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01386
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