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Cell of Origin Susceptibility to Glioblastoma Formation Declines with Neural Lineage Restriction
The contribution of lineage identity and differentiation state to malignant transformation is controversial. We previously showed that adult neural stem and early progenitor cells give origin to glioblastoma (GBM). Here, we systematically assessed the tumor-initiating potential of adult neural popul...
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| Pubblicato in: | Nat Neurosci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6594191/ https://ncbi.nlm.nih.gov/pubmed/30778149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0333-8 |
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