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Cell of Origin Susceptibility to Glioblastoma Formation Declines with Neural Lineage Restriction

The contribution of lineage identity and differentiation state to malignant transformation is controversial. We previously showed that adult neural stem and early progenitor cells give origin to glioblastoma (GBM). Here, we systematically assessed the tumor-initiating potential of adult neural popul...

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Vydáno v:Nat Neurosci
Hlavní autoři: Llaguno, Sheila Alcantara, Sun, Daochun, Pedraza, Alicia, Vera, Elsa, Wang, Zilai, Burns, Dennis K., Parada, Luis F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594191/
https://ncbi.nlm.nih.gov/pubmed/30778149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0333-8
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