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Cell of Origin Susceptibility to Glioblastoma Formation Declines with Neural Lineage Restriction

The contribution of lineage identity and differentiation state to malignant transformation is controversial. We previously showed that adult neural stem and early progenitor cells give origin to glioblastoma (GBM). Here, we systematically assessed the tumor-initiating potential of adult neural popul...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Llaguno, Sheila Alcantara, Sun, Daochun, Pedraza, Alicia, Vera, Elsa, Wang, Zilai, Burns, Dennis K., Parada, Luis F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594191/
https://ncbi.nlm.nih.gov/pubmed/30778149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0333-8
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