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Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

Malignant astrocytomas are infiltrative and incurable brain tumors. Despite profound therapeutic implications, the identity of the cell(s) of origin has not been rigorously determined. We previously reported mouse models based on conditional inactivation of human astrocytoma-relevant tumor suppresso...

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書誌詳細
主要な著者: Alcantara Llaguno, Sheila, Chen, Jian, Kwon, Chang-Hyuk, Jackson, Erica L., Li, Yanjiao, Burns, Dennis K., Alvarez-Buylla, Arturo, Parada, Luis F.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650425/
https://ncbi.nlm.nih.gov/pubmed/19111880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.12.006
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