MCPH1 is essential for cellular adaptation to the G(2)-phase decatenation checkpoint

Cellular checkpoints controlling entry into mitosis monitor the integrity of the DNA and delay mitosis onset until the alteration is fully repaired. However, this canonical response can weaken, leading to a spontaneous bypass of the checkpoint, a process referred to as checkpoint adaptation. Here, w...

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Bibliografiska uppgifter
I publikationen:FASEB J
Huvudupphovsmän: Arroyo, María, Kuriyama, Ryoko, Guerrero, Israel, Keifenheim, Daniel, Cañuelo, Ana, Calahorra, Jesús, Sánchez, Antonio, Clarke, Duncan J., Marchal, J. Alberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Federation of American Societies for Experimental Biology 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593890/
https://ncbi.nlm.nih.gov/pubmed/30964711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802009RR
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