MCPH1 is essential for cellular adaptation to the G(2)-phase decatenation checkpoint

Cellular checkpoints controlling entry into mitosis monitor the integrity of the DNA and delay mitosis onset until the alteration is fully repaired. However, this canonical response can weaken, leading to a spontaneous bypass of the checkpoint, a process referred to as checkpoint adaptation. Here, w...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Arroyo, María, Kuriyama, Ryoko, Guerrero, Israel, Keifenheim, Daniel, Cañuelo, Ana, Calahorra, Jesús, Sánchez, Antonio, Clarke, Duncan J., Marchal, J. Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593890/
https://ncbi.nlm.nih.gov/pubmed/30964711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802009RR
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