MCPH1 is essential for cellular adaptation to the G(2)-phase decatenation checkpoint

Cellular checkpoints controlling entry into mitosis monitor the integrity of the DNA and delay mitosis onset until the alteration is fully repaired. However, this canonical response can weaken, leading to a spontaneous bypass of the checkpoint, a process referred to as checkpoint adaptation. Here, w...

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Bibliographic Details
Published in:FASEB J
Main Authors: Arroyo, María, Kuriyama, Ryoko, Guerrero, Israel, Keifenheim, Daniel, Cañuelo, Ana, Calahorra, Jesús, Sánchez, Antonio, Clarke, Duncan J., Marchal, J. Alberto
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2019
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593890/
https://ncbi.nlm.nih.gov/pubmed/30964711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802009RR
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