Influence of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib: A Randomized Crossover Pharmacokinetic Study

Regorafenib exposure could potentially be influenced by an interaction with acid‐reducing drugs. In this crossover trial, patients were randomized into two sequence groups consisting of three phases: regorafenib intake alone, regorafenib with concomitant esomeprazole, and regorafenib with esomeprazo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: de Man, Femke M., Hussaarts, Koen G.A.M., de With, Mirjam, Oomen‐de Hoop, Esther, de Bruijn, Peter, van Halteren, Henk K., van der Burg‐de Graauw, Nicole C.H.P., Eskens, Ferry A.L.M., van Gelder, Teun, van Leeuwen, Roelof W.F., Mathijssen, Ron H.J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593619/
https://ncbi.nlm.nih.gov/pubmed/30570132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1331
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados