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Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system

BACKGROUND: Complete and contiguous genome assemblies greatly improve the quality of subsequent systems-wide functional profiling studies and the ability to gain novel biological insights. While a de novo genome assembly of an isolated bacterial strain is in most cases straightforward, more informat...

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Veröffentlicht in:BMC Microbiol
Hauptverfasser: Somerville, Vincent, Lutz, Stefanie, Schmid, Michael, Frei, Daniel, Moser, Aline, Irmler, Stefan, Frey, Jürg E., Ahrens, Christian H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593500/
https://ncbi.nlm.nih.gov/pubmed/31238873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1500-0
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