Pushing the limits of de novo genome assembly for complex prokaryotic genomes harboring very long, near identical repeats

Generating a complete, de novo genome assembly for prokaryotes is often considered a solved problem. However, we here show that Pseudomonas koreensis P19E3 harbors multiple, near identical repeat pairs up to 70 kilobase pairs in length, which contained several genes that may confer fitness advantage...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Schmid, Michael, Frei, Daniel, Patrignani, Andrea, Schlapbach, Ralph, Frey, Jürg E, Remus-Emsermann, Mitja N P, Ahrens, Christian H
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158609/
https://ncbi.nlm.nih.gov/pubmed/30137508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky726
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