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Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells

Naive CD4(+) T cells are an example of dynamic cell homeostasis: T cells need to avoid autoreactivity while constantly seeing self-peptides, yet they must be primed to react to foreign antigens during infection. The instructive signals that balance this primed yet quiescent state are unknown. Intera...

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Detalles Bibliográficos
Publicado en:Cell Rep
Autores principales: Myers, Darienne R., Norlin, Emilia, Vercoulen, Yvonne, Roose, Jeroen P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593126/
https://ncbi.nlm.nih.gov/pubmed/31067469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.037
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