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Iron Deposition Leads to Hyperphosphorylation of Tau and Disruption of Insulin Signaling
Iron deposition in the brain is an early issue in Alzheimer's disease (AD). However, the pathogenesis of iron-induced pathological changes in AD remains elusive. Insulin resistance in brains is an essential feature of AD. Previous studies determined that insulin resistance is involved in the de...
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| Udgivet i: | Front Neurol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6593079/ https://ncbi.nlm.nih.gov/pubmed/31275224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.00607 |
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