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Inhibition of STAT3 activation mediated by toll‐like receptor 4 attenuates angiotensin II‐induced renal fibrosis and dysfunction

BACKGROUND AND PURPOSE: Hypertension adversely affects the kidney and is the second leading cause of kidney failure. Overproduction of angiotensin II greatly contributes to the progression of hypertensive kidney disease. Angiotensin II has recently been shown to activate STAT3 in cardiovascular cell...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Xu, Zheng, Zou, Chunpeng, Yu, Weihui, Xu, Sujing, Huang, Lan, Khan, Zia, Wang, Jingying, Liang, Guang, Wang, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592868/
https://ncbi.nlm.nih.gov/pubmed/30958891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14686
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