Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

Objectives: Intervertebral disc degeneration (IDD) is widely accepted as a cause of low back pain and related degenerative musculoskeletal disorders. Nucleus pulposus (NP) cell apoptosis which is related to excessive endoplasmic reticulum (ER) stress in the intervertebral disc (IVD) could aggravate...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Liao, Zhiwei, Luo, Rongjin, Li, Gaocai, Song, Yu, Zhan, Shengfeng, Zhao, Kangcheng, Hua, Wenbin, Zhang, Yukun, Wu, Xinghuo, Yang, Cao
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592170/
https://ncbi.nlm.nih.gov/pubmed/31281533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33638
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