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In Vivo Pharmacodynamic Profile of Ceftibuten-Clavulanate Combination against Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in the Murine Thigh Infection Model

Ceftibuten-clavulanate (CTB-CLA) is a novel β-lactam–β-lactamase combination with potential utility for the management of urinary tract infections caused by extended-spectrum-β-lactamase (ESBL)-producing organisms. We examined the pharmacodynamics of the combination against 25 Enterobacteriaceae exp...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Abdelraouf, Kamilia, Stainton, Sean M., Nicolau, David P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591625/
https://ncbi.nlm.nih.gov/pubmed/31061165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00145-19
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