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The Essential Role of Hypermutation in Rapid Adaptation to Antibiotic Stress
A common outcome of antibiotic exposure in patients and in vitro is the evolution of a hypermutator phenotype that enables rapid adaptation by pathogens. While hypermutation is a robust mechanism for rapid adaptation, it requires trade-offs between the adaptive mutations and the more common “hitchhi...
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| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6591599/ https://ncbi.nlm.nih.gov/pubmed/31036684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00744-19 |
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